An anti-estrogenic lignan glycoside, tracheloside, from seeds of Carthamus tinctorius.
نویسندگان
چکیده
The lignan glycoside, tracheloside, was isolated from seeds of Carthamus tinctorius (Compositae) as an anti-estrogenic principle against cultured Ishikawa cells by employing a bioassay-linked HPLC-ELSD method. Tracheloside significantly decreased the activity of alkaline phosphatase (AP), an estrogen-inducible marker enzyme, with an IC(50) value of 0.31 microg/ml, a level of inhibition comparable to that of tamoxifen (IC(50) = 0.43 microg/ml).
منابع مشابه
Isocartormin, a novel quinochalcone C-glycoside from Carthamus tinctorius
A new semi-quinonechalcone C-glycoside isocartormin along with cartormin and safflomin C were isolated from the water extract of Carthamus tinctorius L. The structure of isocartormin was determined by extensive analysis of HR-MS, 1D- and 2D NMR data, and by comparison with those of cartormin reported previously by our group. Isocartormin was identified as a diastereoisomer of cartormin with a r...
متن کاملStudy of Anti-Nutritive Factors in Some New Varieties of Oil Seeds
Oil seeds are an important source of protein in many developing countries. However this protein is not readily available because of anti-nutrients, hence information on the content of anti-nutrients is required. The objective of the study was to determine the status of anti-nutritive factors in some new varieties of oil seeds, viz Sunflower ( Helianths annus ) LSF -11, Sunflower ( Helianths ann...
متن کاملSafflower (Carthamus tinctorius) seeds and oil meal | Feedipedia
Safflower, false saffron [English]; cártamo, alazor, azafrán bastardo, azafranillo [Spanish]; carthame des teinturiers, safran des teinturiers, safran bâtard [French]; açafrão-bastardo [Portuguese]; saffloer [Dutch]; Färberdistel, saflor [German]; kesumba [Indonesian/Javanese]; cartamo, zafferanone [Italian]; aspir [Turkish]; [Amharic]; رفصع [Arabic]; [Bengali]; 红花 [Chinese]; עירח [Hebrew]; ベニバ...
متن کاملInteraction of Carthamus tinctorius lignan arctigenin with the binding site of tryptophan-degrading enzyme indoleamine 2,3-dioxygenase☆
Mediterranean Carthamus tinctorius (Safflower) is used for treatment of inflammatory conditions and neuropsychiatric disorders. Recently C. tinctorius lignans arctigenin and trachelogenin but not matairesinol were described to interfere with the activity of tryptophan-degrading enzyme indoleamine 2,3-dioxygenase (IDO) in peripheral blood mononuclear cells in vitro. We examined a potential direc...
متن کاملA novel and potent biological antioxidant, Kinobeon A, from cell culture of safflower.
Kinobeon A was originally isolated from cultured cells of safflower (Carthamus tinctorius L., Compositae). It had never previously been directly isolated from safflower or other plants, animals or microorganisms. In this report, we demonstrate the anti-oxidative effects of kinobeon A and compare the results with those two known natural antioxidants, lignan (nordihydroguaiaretic acid) and querce...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 70 11 شماره
صفحات -
تاریخ انتشار 2006